Mannose‐capped lipoarabinomannan‐induced B10 cells decrease severity of dextran sodium sulphate‐induced inflammatory bowel disease in mice
نویسندگان
چکیده
منابع مشابه
INFLAMMATORY BOWEL DISEASE Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium
Background: Several animal models for human ulcerative colitis (UC) associated neoplasia have been reported. However, most neoplasias developed in these models have morphological and genetic characteristics different from UC associated neoplasia. Aims: To establish a new colitis associated neoplasia model in p53 deficient mice by treatment with dextran sulphate sodium (DSS). Methods: DSS coliti...
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Previous work has suggested that the LIGHT-TR2 costimulatory pathway plays a role in the acute and chronic stages of dextran sulfate sodium (DSS)-induced colitis [Steinberg et al. (2008); Wang et al. (2005)]. To clarify the role of TNFR-related 2 (TR2) signaling in the maintenance of intestinal homeostasis, we generated a TR2 knock-out (KO) mouse. Using DSS to induce colitis, we compared the co...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2019
ISSN: 0300-9475,1365-3083
DOI: 10.1111/sji.12843